Histochemistry of the Neuroglia and Myelin in Experimental Cerebral Oedema.

Neuroglia and the myelin-bearing cell: a symposium. Histochemistry of neuroglia and myelin breakdown.

The effect of cabergoline and levetiracetam on the histological and stereological structure of the cerebellar cortex, hippocampal and cerebellum in a model of PTZ-induced seizure kindling in rats

Background: Seizure is a chronic neurological disease that may have non-neurological origins such as astrocytes and microglia. Objective: The aim of this study was to investigate the effect of alone and co-administration of cabergoline and levetiracetam on the histological and stereological structure of the cerebral cortex, hippocampus and cerebellum following chronic seizures in rat. Methods...

A novel fluorescent probe that is brain permeable and selectively binds to myelin.

Myelin is a multilayered glial cell membrane that forms segmented sheaths around large-caliber axons of both the central nervous system (CNS) and peripheral nervous system (PNS). Myelin covering insures rapid and efficient transmission of nerve impulses. Direct visual assessment of local changes of myelin content in vivo could greatly facilitate diagnosis and therapeutic treatments of myelin-re...

Effect of methylprednisolone on the axonal impairment accompanying cellular brain oedema induced by water intoxication in rats.

OBJECTIVES Our previous experiments proved that methylprednisolone (MP) can significantly reduce axonal impairment accompanying extracellular oedema induced by the osmotic challenge (load) on the blood-brain barrier (BBB). The aim of the present work was to identify whether MP can affect myelin impairment accompanying intracellular oedema induced by water intoxication. METHODS For induction o...

اثر فاکتور مهار کننده لوکمیا بر بیان پروتئین اصلی میلین، Olig1 و Olig2 در کورتکس مغز موش‌های مبتلا به مالتیپل اسکلروزیس القا شده با Cuprizone

Background and purpose: Oligodendrocytes are responsible for myelin synthesis in the central nervous system (CNS). Olig1 and Olig2 play an important role in regulating the development of oligodendrocyte precursor cells (OLPs). Myelin basic protein (MBP) is the main component of myelin sheath. Leukemia inhibitory factor (LIF) has an important role in myelination and pathology of multiple scleros...